Brain and immune system: KURU disease a toxicological process?

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Submitted: April 17, 2018
Published: May 3, 2018
DOI: 10.29328/journal.jnnd.1001010
Keywords:
Prion disease pathogenesis, Transmissible spongiform encephalopathy, Innate immune system brain disease, Neurodegenerative disease

Main Article Content

Luisetto M
Applied Pharmacologist, Europeans Specialist Lab Medicine, Independent Researcher, Italy
Behzad Nili-Ahmadabadi
Pharm D/Phd Innovative Pharmaceutical Product Development Specialist, USA
Ghulam Rasool Mashori
Department of Medical and Health Sciences for Woman, Peoples University of Medical and Health Sciences for Women, Pakistan
Ahmed Yesvi
Founder and President Yugen Research Organization (YRO) Independent Researcher Bangladesh
Ram Kumar Sahu
Assistant Professor Columbia Institute of Pharmacy, Tekari, Raipur, India
Heba Nasser
PharmD PhD in Microbiology and Immunology, Faculty Member at Heliopolis University, Egypt
Cabianca luca
Biomedical Laboratory, Turin, Italy
Farhan Ahmad Khan
Professor and Head, Department of Pharmacology, AIMSRC, Udaipur, Rajasthan, India

Abstract

Starting from observation of pathogenesis of KURU disease we try to investigate the immunologic role played by central nervous systems. A deeply knowledge in the transmission model of this pathology can be an imaging/diagnostic tool to Verify the progression of this prion molecule from gastro intestinal systems to the brain. (After cannibalistic behavior). The prions can be considered a sort of trace ant in KURU to monitoring this process and immune- brain relationship. Interesting information can be obtained useful to produce new pharmacological strategies in some other degenerative brain disease involving innate immune system activation.

Article Details

M, L., Nili-Ahmadabadi, B., Rasool Mashori, G., Yesvi, A., Sahu, R. K., Nasser, H., … Ahmad Khan, F. (2018). Brain and immune system: KURU disease a toxicological process?. Journal of Neuroscience and Neurological Disorders, 2(1), 014–027. https://doi.org/10.29328/journal.jnnd.1001010
Research Articles

Copyright (c) 2018 Luisetto M, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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